SETIS™ is a novel concept within TIS technology, using the Twin-bottles principle of two connected vessels (plant material and growth media vessels). Most of the problems and disadvantages of either the commercialized and self-built TIS bioreactors have been solved. Every detail of SETIS™ has been designed to fulfil the requirements of both, plant material and end user. TIS technology has been highly optimized, developing the ideal TIS system for biomass and massive plant micropropagation. Standard, ready-to-use, simple, durable, secure and optimal design. This is SETIS™ SETIS™ has a very simple and safe setup, with a minimum of parts compared to any other bioreactor. Only six components to have a 'state-of-the-art' bioreactor.